Vitamin K1 (CAS: 84-80-0)

Model:VK1-Pure98 | CAS: 84-80-0 | Purity: ≥97.0% Oil / 1% - 5% CWD Powder (USP/EP Grade)

Superpharmagroup is a leading Vitamin K1 manufacture and trusted supplier offering high purity CAS 84-80-0 Phytomenadione. Available in clear viscous oil and microencapsulated water-dispersible powder, our Vitamin K1 delivers high biological activity and excellent formulation stability.

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Product Description

Physical & Chemical Properties

Property Item	Specification Standard
Product Name	Vitamin K1 / Phytomenadione / Phylloquinone
CAS Number	84-80-0
Chemical Formula	C31H46O2
Molecular Weight	450.70 g/mol
Appearance	Clear, viscous, yellow to orange-yellow oil / Free-flowing yellowish powder
Assay / Potency	Pure Oil Grade (≥97.0% - 103.0%) / Diluted CWD Powder (1.0% to 5.0%)
Trans-Isomer Ratio	High Trans-Isomer (≥90.0% Active Biological Configuration)
Refractive Index	1.523 – 1.526
Solubility	Soluble in fatty oils, chloroform, and ether; insoluble in water
Grade Standard	USP / EP / BP / Food Grade / Pharma Grade

Technical & Quality Advantages of Vitamin K1 (CAS: 84-80-0)

High Trans-Isomer Ratio for Maximum Bioactivity: Features strict stereospecific control to ensure trans-isomer ratio ≥90.0%. The biologically active trans-configuration maximizes prothrombin conversion and blood coagulation support compared to inactive cis-isomers.
Light-Protected Stability & Low Impurity Profile: Processed under amber-light and inert-gas conditions to prevent photodegradation. Retains low menadione and organochlorine solvent residue levels, fully conforming to strict European and US pharmacopeial limits.
Cold Water Dispersible (CWD) Powder Formats: Utilizes advanced double-wall microencapsulation technology to convert oily Vitamin K1 into free-flowing, water-dispersible granules, resolving oil-separation issues in hard capsules, tablets, and drink mixes.
Full Pharmacopeial Monograph Compliance: Exceeds United States Pharmacopeia (USP) and European Pharmacopoeia (EP) specifications, ensuring stable shelf life and reliable batch-to-batch consistency for demanding health formulations.

Key Applications

Dietary & Infant Health Supplements: Essential ingredient in newborn nutritional drops, multivitamin preparations, bone density supplements, and maternal nutrition.
Pharmaceutical & Medical Nutrition: Applied in clinical coagulation therapies, fat emulsion injections, and fortified dairy or nutritional powder formulas.